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Science 6 September 1963:
Vol. 141. no. 3584, p. 899
DOI: 10.1126/science.141.3584.899
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Articles

Impurity in Halothane Anesthetic

Ellis N. Cohen 1, J. Weldon Bellville 1, Herbert Budzikiewicz 2, and Dudley H. Williams 2

1 Department of Anesthesia, Stanford University, Stanford, California
2 Department of Chemistry, Stanford University

A halogenated butene has been isolated from commercially available halothane (Fluothane). Its concentration increases under the conditions in which halothane is commonly used in clinical work.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Aerosol Tissue Adhesive Spray: II. Fate of Freons and Their Acute Topical and Systemic Toxicity.
T. Matsumoto, K. C. Pani, J. J. Kovaric, and H. F. Hamit (1968)
Arch Surg 97, 727-735
   Abstract »    PDF »
Summary of the National Halothane Study: Possible Association Between Halothane Anesthesia and Postoperative Hepatic Necrosis.
Subcommittee on the National Halothane Study of th (1966)
JAMA 197, 775-788
   Abstract »    PDF »
Liver Necrosis Following Anesthesia.
R. HERBER and N. W. SPECHT (1965)
Arch Intern Med 115, 266-272
   Abstract »    PDF »
Council on Drugs.
(1963)
JAMA 186, 144-145
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