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Science 6 September 1963:
Vol. 141. no. 3584, pp. 903 - 905
DOI: 10.1126/science.141.3584.903
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Articles

Low Dose Radiation of the Developing Brain

Samuel P. Hicks 1 and Constance J. D'Amato 1

1 Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan

X-irradiation administered in single doses of 10 to 40 r has a widespread effect on the developing rat brain. It first diminishes the formation of cytoplasmic basophilic material in the nerve cells and inhibits their growth. Single doses of 20 to 40 r cause permanent alterations of individual nerve cells, and interfere with their organization into neuronal assemblies, such as layers of the cerebral cortex.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Behavioral Toxicity of Nitrous Oxide in Rats Following Prenatal Exposure.
P. J. Mullenix, P. A. Moore, and M. S. Tassinari (1986)
Toxicology and Industrial Health 2, 273-287
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Science. ISSN 0036-8075 (print), 1095-9203 (online)