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Science 12 November 2004:
Vol. 306. no. 5699, pp. 1183 - 1185
DOI: 10.1126/science.1103178
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Reports

The Genetic Basis of Singlet Oxygen–Induced Stress Responses of Arabidopsis thaliana

Daniela Wagner,1*{dagger} Dominika Przybyla,1* Roel op den Camp,1 Chanhong Kim,1 Frank Landgraf,1 Keun Pyo Lee,1 Marco Würsch,1 Christophe Laloi,1 Mena Nater,1 Eva Hideg,2 Klaus Apel1{ddagger}

Plants under oxidative stress suffer from damages that have been interpreted as unavoidable consequences of injuries inflicted upon plants by toxic levels of reactive oxygen species (ROS). However, this paradigm needs to be modified. Inactivation of a single gene, EXECUTER1, is sufficient to abrogate stress responses of Arabidopsis thaliana caused by the release of singlet oxygen: External conditions under which these stress responses are observed and the amounts of ROS that accumulate in plants exposed to these environmental conditions do not directly cause damages. Instead, seedling lethality and growth inhibition of mature plants result from genetic programs that are activated after the release of singlet oxygen has been perceived by the plant.

1 Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH-8092 Zurich, Switzerland.
2 Institute of Plant Biology, Biological Research Center, Hungarian Academy of Sciences, H-6701 Szeged, Hungary.



* These authors contributed equally to this work.

{dagger} Deceased 24 February 2004.

{ddagger} To whom correspondence should be addressed. E-mail: klaus.apel{at}ipw.biol.ethz.ch

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