Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 13 May 2005:
Vol. 308. no. 5724, p. 996
DOI: 10.1126/science.1109987

Brevia

Reconstructing the Origin of Andaman Islanders

Kumarasamy Thangaraj,1 Gyaneshwer Chaubey,1 Toomas Kivisild,2 Alla G. Reddy,1 Vijay Kumar Singh,1 Avinash A. Rasalkar,1 Lalji Singh1*

The origin of the Andaman "Negrito" and Nicobar "Mongoloid" populations has been ambiguous. Our analyses of complete mitochondrial DNA sequences from Onges and Great Andaman populations revealed two deeply branching clades that share their most recent common ancestor in founder haplogroup M, with lineages spread among India, Africa, East Asia, New Guinea, and Australia. This distribution suggests that these two clades have likely survived in genetic isolation since the initial settlement of the islands during an out-of-Africa migration by anatomically modern humans. In contrast, Nicobarese sequences illustrate a close genetic relationship with populations from Southeast Asia.

1 Centre for Cellular and Molecular Biology, Hyderabad-500 007, India.
2 Estonian Biocenter, Riia 23, Tartu-51010, Estonia.

* To whom correspondence should be addressed. E-mail: lalji{at}ccmb.res.in

Read the Full Text



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Bayesian coalescent inference of major human mitochondrial DNA haplogroup expansions in Africa.
Q. D Atkinson, R. D Gray, and A. J Drummond (2009)
Proc R Soc B 276, 367-373
   Abstract »    Full Text »    PDF »
Novel Variants in UBE2B Gene and Idiopathic Male Infertility.
V. Suryavathi, A. Khattri, K. Gopal, D. S. Rani, S. Panneerdoss, N. J. Gupta, B. Chakravarty, M. Deenadayal, L. Singh, and K. Thangaraj (2008)
J Androl 29, 564-571
   Abstract »    Full Text »    PDF »
mtDNA Variation Predicts Population Size in Humans and Reveals a Major Southern Asian Chapter in Human Prehistory.
Q. D. Atkinson, R. D. Gray, and A. J. Drummond (2008)
Mol. Biol. Evol. 25, 468-474
   Abstract »    Full Text »    PDF »
Mitochondrial diversity within modern human populations.
R. W. Carter (2007)
Nucleic Acids Res. 35, 3039-3045
   Abstract »    Full Text »    PDF »
Revealing the prehistoric settlement of Australia by Y chromosome and mtDNA analysis.
G. Hudjashov, T. Kivisild, P. A. Underhill, P. Endicott, J. J. Sanchez, A. A. Lin, P. Shen, P. Oefner, C. Renfrew, R. Villems, et al. (2007)
PNAS 104, 8726-8730
   Abstract »    Full Text »    PDF »
Whole-mtDNA Genome Sequence Analysis of Ancient African Lineages.
M. K. Gonder, H. M. Mortensen, F. A. Reed, A. de Sousa, and S. A. Tishkoff (2007)
Mol. Biol. Evol. 24, 757-768
   Abstract »    Full Text »    PDF »
Origin and Expansion of Haplogroup H, the Dominant Human Mitochondrial DNA Lineage in West Eurasia: The Near Eastern and Caucasian Perspective.
U Roostalu, I Kutuev, E-L Loogvali, E Metspalu, K Tambets, M Reidla, E. Khusnutdinova, E Usanga, T Kivisild, and R Villems (2007)
Mol. Biol. Evol. 24, 436-448
   Abstract »    Full Text »    PDF »
Deciphering Past Human Population Movements in Oceania: Provably Optimal Trees of 127 mtDNA Genomes.
M. J. Pierson, R. Martinez-Arias, B. R. Holland, N. J. Gemmell, M. E. Hurles, and D. Penny (2006)
Mol. Biol. Evol. 23, 1966-1975
   Abstract »    Full Text »    PDF »
Going east: new genetic and archaeological perspectives on the modern human colonization of Eurasia..
P. Mellars (2006)
Science 313, 796-800
   Abstract »    Full Text »    PDF »
Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations.
Q.-P. Kong, H.-J. Bandelt, C. Sun, Y.-G. Yao, A. Salas, A. Achilli, C.-Y. Wang, L. Zhong, C.-L. Zhu, S.-F. Wu, et al. (2006)
Hum. Mol. Genet. 15, 2076-2086
   Abstract »    Full Text »    PDF »
The Dazzling Array of Basal Branches in the mtDNA Macrohaplogroup M from India as Inferred from Complete Genomes.
C. Sun, Q.-P. Kong, M. g. Palanichamy, S. Agrawal, H.-J. Bandelt, Y.-G. Yao, F. Khan, C.-L. Zhu, T. K. Chaudhuri, and Y.-P. Zhang (2006)
Mol. Biol. Evol. 23, 683-690
   Abstract »    Full Text »    PDF »
Comment on "Reconstructing the Origin of Andaman Islanders".
M. g. Palanichamy, S. Agrawal, Y.-G. Yao, Q.-P. Kong, C. Sun, F. Khan, T. K. Chaudhuri, and Y.-P. Zhang (2006)
Science 311, 470a
   Abstract »    Full Text »    PDF »
Response to Comment on "Reconstructing the Origin of Andaman Islanders".
K. Thangaraj, G. Chaubey, T. Kivisild, A. G. Reddy, V. K. Singh, A. A. Rasalkar, and L. Singh (2006)
Science 311, 470b
   Abstract »    Full Text »    PDF »
Ancient mitochondrial M haplogroups identified in the Southwest Pacific.
D. A. Merriwether, J. A. Hodgson, F. R. Friedlaender, R. Allaby, S. Cerchio, G. Koki, and J. S. Friedlaender (2005)
PNAS 102, 13034-13039
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)