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Science 6 September 1963:
Vol. 141. no. 3584, pp. 930 - 932
DOI: 10.1126/science.141.3584.930
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Articles

Pulmonary Edema as a Consequence of Hypothalamic Lesions in Rats

Robert W. Reynolds 1

1 Department of Psychology, University of California, Santa Barbara, University

Rats were observed for the incidence of pulmonary edema after the placement of hypothalamic lesions by radio frequency thermocoagulation or d-c electrolysis. In the animals with electrolytic lesions, 31 percent died with pulmonary edema and marked signs were observed in another 20 percent. Moderate transient signs appeared in only 3.7 percent of the animals with radio-frequency lesions, and there were no deaths attributable to this syndrome in this group. These results suggest that this syndrome is an irritative consequence of the electrolytic lesion process rather than a "release" phenomenon.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Postictal Pulmonary Edema: Report of a Case.
K. Teplinsky and J. Hall (1986)
Arch Intern Med 146, 801-802
   Abstract »    PDF »
Sleep Suppression after Basal Forebrain Lesions in the Cat.
D. J. McGinty and M. B. Sterman (1968)
Science 160, 1253-1255
   Abstract »    PDF »
Hypothalamic Lesions by Electrocauterization: Disinhibition of Feeding and Self-Stimulation.
B. G. Hoebel (1965)
Science 149, 452-453
   Abstract »    PDF »


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