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Science 24 December 2004:
Vol. 306. no. 5705, p. 2172
DOI: 10.1126/science.306.5705.2172

News of the Week

GENETICS:
A Ruff Theory of Evolution: Gene Stutters Drive Dog Shape

Elizabeth Pennisi

Armed with DNA from more than 100 dogs, scientists have now shown that slight differences in the lengths of certain genes involved in development can transform a collie nose into a puglike one and even change the number of toes in one breed. Furthermore, their study, reported in the 28 December Proceedings of the National Academy of Sciences, drives home the potential evolutionary importance of repetitive DNA sequences called tandem repeats.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)