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Early clinical trials have indicated that a potential new class of AIDS drugs, known as the protease inhibitors, may both decrease the amount of HIV in patients' blood and possibly decrease disease and death by as much as 50%. Those findings, combined with others showing that people with lower viral loads fare better than people who have a lot of virus in their blood, have encouraged AIDS researchers, although given the previous ups and downs of the first AIDS drug, AZT, they remain cautious about the future prospects of the protease inhibitors.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)