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Science 8 December 2000:
Vol. 290. no. 5498, pp. 1867 - 1869
DOI: 10.1126/science.290.5498.1867b
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News of the Week

INFECTIOUS DISEASES:
Polio Outbreak Raises Questions About Vaccine

Liese Greensfelder

A small cluster of polio cases in the Dominican Republic and Haiti marks both the first polio outbreak in the Western Hemisphere in more than 9 years and the first reliable report that a vaccine-derived polio strain may have reverted to a virulent form and spread contagiously. Although a massive vaccination campaign already in the works is expected to contain the outbreak, the unusual incident raises troubling questions about a vaccine that has been in widespread use for nearly 40 years.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)