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Science 2 January 2004:
Vol. 303. no. 5654, pp. 23 - 25
DOI: 10.1126/science.303.5654.23a
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News of the Week

CANCER RESEARCH:
Drug Candidate Bolsters Cell's Tumor Defenses

Jean Marx

In work published online by Science this week (www.sciencemag.org/cgi/content/abstract/1092472), a research team identifies a class of small molecules that can turn the activity of the p53 tumor-suppressor gene, which is inactivated in most human cancers, back on. They may thus be good candidates for drugs that shrink cancerous tumors.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)