Brain Disease

Problems and Progress

Peter Stern and Laura Helmuth
Science 31 October 2003: 807.
Summary »|   PDF »|  

News

In Sickness or in Health?

Laura Helmuth
Science 31 October 2003: 808-810.
Summary »|   Full Text »|   PDF »|  

Future Brightening for Depression Treatments

Constance Holden
Science 31 October 2003: 810-813.
Summary »|   Full Text »|   PDF »|  

Viewpoint

Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?

Huda Y. Zoghbi
Science 31 October 2003: 826-830.
Abstract »|   Full Text »|   PDF »|  

Reviews

Games Played by Rogue Proteins in Prion Disorders and Alzheimer's Disease

Adriano Aguzzi and Christian Haass
Science 31 October 2003: 814-818.
Abstract »|   Full Text »|   PDF »|  

Molecular Pathways of Neurodegeneration in Parkinson's Disease

Ted M. Dawson and Valina L. Dawson
Science 31 October 2003: 819-822.
Abstract »|   Full Text »|   PDF »|  

The Genetics of Adult-Onset Neuropsychiatric Disease: Complexities and Conundra?

James L. Kennedy, Lindsay A. Farrer, Nancy C. Andreasen, Richard Mayeux, and Peter St George-Hyslop
Science 31 October 2003: 822-826.
Abstract »|   Full Text »|   PDF »|  

Looking Backward to Move Forward: Early Detection of Neurodegenerative Disorders

Steven T. DeKosky and Kenneth Marek
Science 31 October 2003: 830-834.
Abstract »|   Full Text »|   PDF »|  

Immunotherapeutic Approaches to Alzheimer's Disease

Alon Monsonego and Howard L. Weiner
Science 31 October 2003: 834-838.
Abstract »|   Full Text »|   PDF »|  

This Week in Science

Editor summaries of this week's papers.
Science 31 October 2003: 741.
|Full Text »

Editorial:
Genetic Discrimination: Time to Act

Francis S. Collins and James D. Watson
Science 31 October 2003: 745.
Summary »|   PDF »|  

Editors' Choice

Highlights of the recent literature.
Science 31 October 2003: 747.
|Full Text »

NetWatch

Best of the Web in science.
Science 31 October 2003: 757.
|Full Text »

 AAAS News & Notes

Science 31 October 2003: 802-805.

 NEW PRODUCTS

Science 31 October 2003: 895.

News of the Week

BIOMEDICAL POLITICS:
NIH Roiled by Inquiries Over Grants Hit List

Jocelyn Kaiser
Science 31 October 2003: 758.
Summary »|   Full Text »|   PDF »|  

GLACIOLOGY:
Warmer Ocean Could Threaten Antarctic Ice Shelves

Jocelyn Kaiser
Science 31 October 2003: 759.
Summary »|   Full Text »|   PDF »|  

FORENSIC GEOCHEMISTRY:
Isotopic Data Pinpoint Iceman's Origins

Constance Holden
Science 31 October 2003: 759-761.
Summary »|   Full Text »|   PDF »|  

COSMOLOGY:
Galaxy Maps Support Theory That the Universe Is Flying to Pieces

Charles Seife
Science 31 October 2003: 762-763.
Summary »|   Full Text »|   PDF »|  

ENERGY RESEARCH:
DOE Told to Make Its Science More Visible

David Malakoff
Science 31 October 2003: 762.
Summary »|   Full Text »|   PDF »|  

MEDICINE:
In a First, Infected Mice Recover From Prion Disease

Jennifer Couzin
Science 31 October 2003: 763-765.
Summary »|   Full Text »|   PDF »|  

ENDANGERED SPECIES:
NRC Backs Ecosystem-Wide Changes to Save Klamath Fish

Robert F. Service
Science 31 October 2003: 765.
Summary »|   Full Text »|   PDF »|  

ScienceScope

Science 31 October 2003: 761.
|Full Text »

Random Samples

Science 31 October 2003: 777.
|Full Text »

News Focus

INFECTIOUS DISEASES:
Search for SARS Origins Stalls

Martin Enserink and Dennis Normile
Science 31 October 2003: 766-767.
Summary »|   Full Text »|   PDF »|  

INFECTIOUS DISEASES:
Unexplained False Alarm May Hold Lessons

Martin Enserink
Science 31 October 2003: 767.
Summary »|   Full Text »|   PDF »|  

ECOLOGY:
Methuselahs in Our Midst

Kevin Krajick
Science 31 October 2003: 768-769.
Summary »|   Full Text »|   PDF »|  

PALEONTOLOGY:
Peering Into Ancient Ears

Erik Stokstad
Science 31 October 2003: 770-771.
Summary »|   Full Text »|   PDF »|  

MARINE RESEARCH:
Scientists Counting on Census to Reveal Marine Biodiversity

David Malakoff
Science 31 October 2003: 773.
Summary »|   Full Text »|   PDF »|  

SYMBIOSIS:
Fast Friends, Sworn Enemies

Elizabeth Pennisi
Science 31 October 2003: 774-775.
Summary »|   Full Text »|   PDF »|  

Letters

This Week's Letters

Science 31 October 2003: 781.
Summary »|   PDF »|  

 Tracking Children's Health to Age 21

E. Stephen Edwards, Nancy Green, Carol J. Henry, Philip J. Landrigan, and Daniel Swartz
Science 31 October 2003: 781.
Full Text »|   PDF »|  

 Agricultural IP and the Public Sector

Jorge A. Huete-Pérez;, David Korn, Stephen Heinig;, Gordon Conway, and Rip Rapson
Science 31 October 2003: 781-783.
Full Text »|   PDF »|  

 Forgery: Prediction's Vile Twin

Joachim L. Dagg
Science 31 October 2003: 783-784.
Full Text »|   PDF »|  

 CORRECTIONS AND CLARIFICATIONS

Science 31 October 2003: 784.
Full Text »|   PDF »|  

Books et al.

PHILOSOPHY OF SCIENCE:
Conciliation, Gould's Last Discourse

Robert N. Proctor
Science 31 October 2003: 785.
Summary »|   Full Text »|   PDF »|  

 Books Received

Science 31 October 2003: 785.

Essays on Science and Society

EPPENDORF 2003 PRIZE-WINNING ESSAY:
Ubiquitin and the Deconstruction of Synapses

Michael D. Ehlers
Science 31 October 2003: 800-801.
Summary »|   Full Text »|   PDF »|  

 2003 Grand Prize Winner

Science 31 October 2003: 801.
Full Text »|   PDF »|  

Policy Forum

INFORMATION SCIENCE:
Going, Going, Gone: Lost Internet References

Robert P. Dellavalle, Eric J. Hester, Lauren F. Heilig, Amanda L. Drake, Jeff W. Kuntzman, Marla Graber, and Lisa M. Schilling
Science 31 October 2003: 787-788.
Summary »|   Full Text »|   PDF »|   Supporting Online Material »|  

Perspectives

NEUROSCIENCE:
Illusions and Perceived Images in the Primate Brain

Ulf T. Eysel
Science 31 October 2003: 789-791.
Summary »|   Full Text »|   PDF »|  

OCEAN SCIENCE:
Enhanced: Who Threw That Snowball?

David Archer
Science 31 October 2003: 791-792.
Summary »|   Full Text »|   PDF »|  

CHEMISTRY:
Ionic Liquids--Solvents of the Future?

Robin D. Rogers and Kenneth R. Seddon
Science 31 October 2003: 792-793.
Summary »|   Full Text »|   PDF »|  

MOLECULAR BIOLOGY:
MeCP2 Repression Goes Nonglobal

Robert Klose and Adrian Bird
Science 31 October 2003: 793-795.
Summary »|   Full Text »|   PDF »|  

PHYSICS:
Searching for Gravity's Hidden Strength

Jonathan L. Feng
Science 31 October 2003: 795-797.
Summary »|   Full Text »|   PDF »|  

ECOLOGY:
Vole Stranglers and Lemming Cycles

Peter J. Hudson and Ottar N. Bjørnstad
Science 31 October 2003: 797-798.
Summary »|   Full Text »|   PDF »|  

Brevia

 -Synuclein Locus Triplication Causes Parkinson's Disease

A. B. Singleton, M. Farrer, J. Johnson, A. Singleton, S. Hague, J. Kachergus, M. Hulihan, T. Peuralinna, A. Dutra, R. Nussbaum, S. Lincoln, A. Crawley, M. Hanson, D. Maraganore, C. Adler, M. R. Cookson, M. Muenter, M. Baptista, D. Miller, J. Blancato, J. Hardy, and K. Gwinn-Hardy
Science 31 October 2003: 841.
Full Text »|   PDF »|   Supporting Online Material »|  

Research Article

Empirical Analysis of Transcriptional Activity in the Arabidopsis Genome

Kayoko Yamada, Jun Lim, Joseph M. Dale, Huaming Chen, Paul Shinn, Curtis J. Palm, Audrey M. Southwick, Hank C. Wu, Christopher Kim, Michelle Nguyen, Paul Pham, Rosa Cheuk, George Karlin-Newmann, Shirley X. Liu, Bao Lam, Hitomi Sakano, Troy Wu, Guixia Yu, Molly Miranda, Hong L. Quach, Matthew Tripp, Charlie H. Chang, Jeong M. Lee, Mitsue Toriumi, Marie M. H. Chan, Carolyn C. Tang, Courtney S. Onodera, Justine M. Deng, Kenji Akiyama, Yasser Ansari, Takahiro Arakawa, Jenny Banh, Fumika Banno, Leah Bowser, Shelise Brooks, Piero Carninci, Qimin Chao, Nathan Choy, Akiko Enju, Andrew D. Goldsmith, Mani Gurjal, Nancy F. Hansen, Yoshihide Hayashizaki, Chanda Johnson-Hopson, Vickie W. Hsuan, Kei Iida, Meagan Karnes, Shehnaz Khan, Eric Koesema, Junko Ishida, Paul X. Jiang, Ted Jones, Jun Kawai, Asako Kamiya, Cristina Meyers, Maiko Nakajima, Mari Narusaka, Motoaki Seki, Tetsuya Sakurai, Masakazu Satou, Racquel Tamse, Maria Vaysberg, Erika K. Wallender, Cecilia Wong, Yuki Yamamura, Shiaulou Yuan, Kazuo Shinozaki, Ronald W. Davis, Athanasios Theologis, and Joseph R. Ecker
Science 31 October 2003: 842-846.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Direct Atom-Resolved Imaging of Oxides and Their Grain Boundaries

Zaoli Zhang, Wilfried Sigle, Fritz Phillipp, and Manfred Rühle
Science 31 October 2003: 846-849.
Abstract »|   Full Text »|   PDF »|  

Is the Fragility of a Liquid Embedded in the Properties of Its Glass?

Tullio Scopigno, Giancarlo Ruocco, Francesco Sette, and Giulio Monaco
Science 31 October 2003: 849-852.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Decadal Variation of the Surface Water PCO₂ in the Western and Central Equatorial Pacific

Taro Takahashi, Stewart C. Sutherland, Richard A. Feely, and Catherine E. Cosca
Science 31 October 2003: 852-856.
Abstract »|   Full Text »|   PDF »|  

Larsen Ice Shelf Has Progressively Thinned

Andrew Shepherd, Duncan Wingham, Tony Payne, and Pedro Skvarca
Science 31 October 2003: 856-859.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Carbonate Deposition, Climate Stability, and Neoproterozoic Ice Ages

Andy J. Ridgwell, Martin J. Kennedy, and Ken Caldeira
Science 31 October 2003: 859-862.
Abstract »|   Full Text »|   PDF »|  

Origin and Migration of the Alpine Iceman

Wolfgang Müller, Henry Fricke, Alex N. Halliday, Malcolm T. McCulloch, and Jo-Anne Wartho
Science 31 October 2003: 862-866.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Cyclic Dynamics in a Simple Vertebrate Predator-Prey Community

Olivier Gilg, Ilkka Hanski, and Benoît Sittler
Science 31 October 2003: 866-868.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

A Four-Base Paired Genetic Helix with Expanded Size

Haibo Liu, Jianmin Gao, Stephen R. Lynch, Y. David Saito, Lystranne Maynard, and Eric T. Kool
Science 31 October 2003: 868-871.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Depleting Neuronal PrP in Prion Infection Prevents Disease and Reverses Spongiosis

Giovanna Mallucci, Andrew Dickinson, Jacqueline Linehan, Peter-Christian Klöhn, Sebastian Brandner, and John Collinge
Science 31 October 2003: 871-874.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

Paul S. Changelian, Mark E. Flanagan, Douglas J. Ball, Craig R. Kent, Kelly S. Magnuson, William H. Martin, Bonnie J. Rizzuti, Perry S. Sawyer, Bret D. Perry, William H. Brissette, Sandra P. McCurdy, Elizabeth M. Kudlacz, Maryrose J. Conklyn, Eileen A. Elliott, Erika R. Koslov, Michael B. Fisher, Timothy J. Strelevitz, Kwansik Yoon, David A. Whipple, Jianmin Sun, Michael J. Munchhof, John L. Doty, Jeffrey M. Casavant, Todd A. Blumenkopf, Michael Hines, Matthew F. Brown, Brett M. Lillie, Chakrapani Subramanyam, Chang Shang-Poa, Anthony J. Milici, Gretchen E. Beckius, James D. Moyer, Chunyan Su, Thasia G. Woodworth, Anderson S. Gaweco, Chan R. Beals, Bruce H. Littman, Douglas A. Fisher, James F. Smith, Panayiotis Zagouras, Holly A. Magna, Mary J. Saltarelli, Kimberly S. Johnson, Linda F. Nelms, Shelley G. Des Etages, Lisa S. Hayes, Thomas T. Kawabata, Deborah Finco-Kent, Deanna L. Baker, Michael Larson, Ming-Sing Si, Ricardo Paniagua, John Higgins, Bari Holm, Bruce Reitz, Yong-Jie Zhou, Randall E. Morris, John J. O'Shea, and Dominic C. Borie
Science 31 October 2003: 875-878.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Flexible Retinotopy: Motion-Dependent Position Coding in the Visual Cortex

David Whitney, Herbert C. Goltz, Christopher G. Thomas, Joseph S. Gati, Ravi S. Menon, and Melvyn A. Goodale
Science 31 October 2003: 878-881.
Published online 18 September 2003 [DOI: 10.1126/science.1087839] (in Science Express Reports)
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Optical Imaging of a Tactile Illusion in Area 3b of the Primary Somatosensory Cortex

Li M. Chen, Robert M. Friedman, and Anna W. Roe
Science 31 October 2003: 881-885.
Published online 18 September 2003 [DOI: 10.1126/science.1087846] (in Science Express Reports)
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

Wen G. Chen, Qiang Chang, Yingxi Lin, Alexander Meissner, Anne E. West, Eric C. Griffith, Rudolf Jaenisch, and Michael E. Greenberg
Science 31 October 2003: 885-889.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

Keri Martinowich, Daisuke Hattori, Hao Wu, Shaun Fouse, Fei He, Yan Hu, Guoping Fan, and Yi E. Sun
Science 31 October 2003: 890-893.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

 Comment on Salt-Pump Mechanism for Contaminant Intrusion into Coastal Aquifers

D. R. Lloyd
Science 31 October 2003: 784.
Full Text »|   PDF »|  

 Response to Comment on Salt-Pump Mechanism for Contaminant Intrusion into Coastal Aquifers

Ishai Dror, Bruno Yaron, and Brian Berkowitz
Science 31 October 2003: 784.
Full Text »|   PDF »|