Materials and Biology

Design for Living

Marc Lavine, Valda Vinson, and Robert Coontz
Science 18 November 2005: 1131.
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News

MATERIALS AND BIOLOGY: Nanotechnology Takes Aim at Cancer

Robert F. Service
Science 18 November 2005: 1132-1134.
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Reviews

Exploring and Engineering the Cell Surface Interface

Molly M. Stevens and Julian H. George
Science 18 November 2005: 1135-1138.
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Tissue Cells Feel and Respond to the Stiffness of Their Substrate

Dennis E. Discher, Paul Janmey, and Yu-li Wang
Science 18 November 2005: 1139-1143.
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Rigid Biological Systems as Models for Synthetic Composites

George Mayer
Science 18 November 2005: 1144-1147.
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Inspirations from Biological Optics for Advanced Photonic Systems

Luke P. Lee and Robert Szema
Science 18 November 2005: 1148-1150.
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This Week in Science

Editor summaries of this week's papers.
Science 18 November 2005: 1085.
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Editorial:
Not Just Jobs: ScienceCareers.org

Jim Austin and Donald Kennedy
Science 18 November 2005: 1089.
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Editors' Choice

Highlights of the recent literature.
Science 18 November 2005: 1091.
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NetWatch

Best of the Web in science.
Science 18 November 2005: 1099.
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NEW PRODUCTS

Science 18 November 2005: 1199.
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News of the Week

STEM CELLS: Collaborators Split Over Ethics Allegations

Gretchen Vogel
Science 18 November 2005: 1100.
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U.S. HIGHER EDUCATION: Professor Sues University Over Building He Is Funding

Jennifer Couzin
Science 18 November 2005: 1101-1102.
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POLITICS: Antiterror Law Intrusive, U.K. Academic Groups Warn

Eliot Marshall
Science 18 November 2005: 1101.
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AFRICAN SCIENCE: A Move to Revamp Elite Institutions Across the Continent

Robert Koenig
Science 18 November 2005: 1102.
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INFLUENZA: Meeting Seeks Global Consensus, Highlights Global Disparities

Martin Enserink
Science 18 November 2005: 1103.
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NEUROSCIENCE: Neuroscientists Welcome Dalai Lama With Mostly Open Arms

Yudhijit Bhattacharjee
Science 18 November 2005: 1104.
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TEACHING EVOLUTION: Antievolutionists Win One in Kansas, Lose Eight Seats in Dover

Constance Holden and Yudhijit Bhattacharjee
Science 18 November 2005: 1105.
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ScienceScope

Science 18 November 2005: 1103.
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Random Samples

Science 18 November 2005: 1114.
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News Focus

ENERGY SUPPLIES: Bumpy Road Ahead for World's Oil

Richard A. Kerr
Science 18 November 2005: 1106-1108.
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ENERGY SUPPLIES: If Not Cheap Oil ...

Richard A. Kerr
Science 18 November 2005: 1107.
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DEVELOPMENTAL BASIS OF EVOLUTION MEETING: Hummingbirds Keep Plant Speciation Humming Along

Elizabeth Pennisi
Science 18 November 2005: 1109.
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DEVELOPMENTAL BASIS OF EVOLUTION MEETING: Development Out of Sync

Elizabeth Pennisi
Science 18 November 2005: 1109-1110.
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EDWARD AMES PROFILE: Uncovering the Hidden Paths Of Maine's Threatened Cod

Yudhijit Bhattacharjee
Science 18 November 2005: 1110-1111.
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AVIAN INFLUENZA: Pandemic Skeptics Warn Against Crying Wolf

Dennis Normile
Science 18 November 2005: 1112-1113.
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Letters

This Week's Letters

Science 18 November 2005: 1117.
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 New Directions in Plastic Debris

Richard Thompson, Charles Moore, Anthony Andrady, Murray Gregory, Hideshige Takada, and Stephen Weisberg
Science 18 November 2005: 1117.
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 Preparing for the Worst-Case Scenario

Pui Hong Alex Chung;, Ira M. Longini Jr., and M. Elizabeth Halloran
Science 18 November 2005: 1117-1118.
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 Timing in Collection of Stool Samples

Volker Mai, O. Colin Stine, J. Glenn Morris Jr.;, Paul B. Eckburg, Elisabeth M. Bik, Charles N. Bernstein, Les Dethlefsen, Elizabeth Purdom, Michael Sargent, Steven R. Gill, Karen E. Nelson, and David A. Relman
Science 18 November 2005: 1118.
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 Corrections and Clarifications

Science 18 November 2005: 1119.
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Books et al.

NEUROSCIENCE: Nerves as Chemical Messengers

Arvid Carlsson
Science 18 November 2005: 1120-1121.
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PHILOSOPHY OF SCIENCE: Genomic Meanings

Michael A. Goldman
Science 18 November 2005: 1121.
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Books Received

Science 18 November 2005: 1121.
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Policy Forum

EPIDEMIOLOGY: Enhanced: DNA Identifications After the 9/11 World Trade Center Attack

Leslie G. Biesecker, Joan E. Bailey-Wilson, Jack Ballantyne, Howard Baum, Frederick R. Bieber, Charles Brenner, Bruce Budowle, John M. Butler, George Carmody, P. Michael Conneally, Barry Duceman, Arthur Eisenberg, Lisa Forman, Kenneth K. Kidd, Benoit Leclair, Steven Niezgoda, Thomas J. Parsons, Elizabeth Pugh, Robert Shaler, Stephen T. Sherry, Amanda Sozer, and Anne Walsh
Science 18 November 2005: 1122-1123.
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Perspectives

CELL BIOLOGY: Twists in the Tale of the Aging Yeast

Jasper Rine
Science 18 November 2005: 1124-1125.
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GEOCHEMISTRY: A Stranger in Paradise

Paul F. McMillan
Science 18 November 2005: 1125-1126.
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PALEONTOLOGY: Dinosaurs Dined on Grass

Dolores R. Piperno and Hans-Dieter Sues
Science 18 November 2005: 1126-1128.
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GENETICS: Two Genes Link Two Distinct Psychoses

Akira Sawa and Solomon H. Snyder
Science 18 November 2005: 1128-1129.
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Brevia

Directionally Controlled Fluorescence Emission in Butterflies

Pete Vukusic and Ian Hooper
Science 18 November 2005: 1151.
Butterfly scales contain two-dimensional photonic crystals with a direct reflector, producing an intense fluorescence similar to that of light-emitting diodes. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Research Articles

Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes

Benjamin P. Tu, Andrzej Kudlicki, Maga Rowicka, and Steven L. McKnight
Science 18 November 2005: 1152-1158.
Published online 27 October 2005 [DOI: 10.1126/science.1120499] (in Science Express Research Articles)
Tracking of gene expression in yeast during a 5-hour cycle of respiration and cell division reveals how metabolic processes are segregated in time. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Structure of the Quaternary Complex of Interleukin-2 with Its , ß, and _c Receptors

Xinquan Wang, Mathias Rickert, and K. Christopher Garcia
Science 18 November 2005: 1159-1163.
A hormone activates immune cells by sequentially recruiting two specific receptors and then a common third receptor, forming a high-affinity signaling complex. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Thermodynamics of an Incommensurate Quantum Crystal

P. W. Anderson, W. F. Brinkman, and David A. Huse
Science 18 November 2005: 1164-1166.
Published online 3 November 2005 [DOI: 10.1126/science.1118625] (in Science Express Reports)
A thermodynamic model explains that supersolid ₄He--a solid that flows as a superfluid--is a crystal in which the number of lattice sites mismatches the number of atoms. Abstract »|   Full Text »|   PDF »|  

Porous, Crystalline, Covalent Organic Frameworks

Adrien P. Côté, Annabelle I. Benin, Nathan W. Ockwig, Michael O'Keeffe, Adam J. Matzger, and Omar M. Yaghi
Science 18 November 2005: 1166-1170.
Condensation of organic boron compounds produces useful materials containing large pores that are stable to high temperatures and do not require linking metal atoms. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Bright Infrared Emission from Electrically Induced Excitons in Carbon Nanotubes

Jia Chen, Vasili Perebeinos, Marcus Freitag, James Tsang, Qiang Fu, Jie Liu, and Phaedon Avouris
Science 18 November 2005: 1171-1174.
When paired electrons and holes generated in suspended nanotubes recombine, they emit intense infrared radiation, with an efficiency greater than that of typical light-emitting diodes. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Retention of Xenon in Quartz and Earth's Missing Xenon

Chrystèle Sanloup, Burkhard C. Schmidt, Eva Maria Chamorro Perez, Albert Jambon, Eugene Gregoryanz, and Mohamed Mezouar
Science 18 November 2005: 1174-1177.
Experiments suggest that enough xenon can substitute for silicon in quartz (SiO₂) in the deep crust to explain a marked deficit of xenon in Earth's atmosphere. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Dinosaur Coprolites and the Early Evolution of Grasses and Grazers

Vandana Prasad, Caroline A. E. Strömberg, Habib Alimohammadian, and Ashok Sahni
Science 18 November 2005: 1177-1180.
Silica particles from grass in fossil dung from Cretaceous sauropods suggest that grasses evolved earlier than had been thought, providing food for dinosaurs and early mammals. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Pre- and Postinvasion Defenses Both Contribute to Nonhost Resistance in Arabidopsis

Volker Lipka, Jan Dittgen, Pawel Bednarek, Riyaz Bhat, Marcel Wiermer, Monica Stein, Jörn Landtag, Wolfgang Brandt, Sabine Rosahl, Dierk Scheel, Francisco Llorente, Antonio Molina, Jane Parker, Shauna Somerville, and Paul Schulze-Lefert
Science 18 November 2005: 1180-1183.
A robust defense system that protects plants from fungal invasion depends on both a cellular enzyme and a signaling pathway that leads to death of infected cells. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

GTF2IRD1 in Craniofacial Development of Humans and Mice

May Tassabehji, Peter Hammond, Annette Karmiloff-Smith, Pamela Thompson, Snorri S. Thorgeirsson, Marian E. Durkin, Nicholas C. Popescu, Timothy Hutton, Kay Metcalfe, Agnes Rucka, Helen Stewart, Andrew P. Read, Mark Maconochie, and Dian Donnai
Science 18 November 2005: 1184-1187.
Published online 3 November 2005 [DOI: 10.1126/science.1116142] (in Science Express Reports)
Of the 28 genes deleted in the complex human disorder Williams-Beuren syndrome, one has been identified as responsible for the facial abnormalities seen in patients. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

J. Kirsty Millar, Benjamin S. Pickard, Shaun Mackie, Rachel James, Sheila Christie, Sebastienne R. Buchanan, M. Pat Malloy, Jennifer E. Chubb, Elaine Huston, George S. Baillie, Pippa A. Thomson, Elaine V. Hill, Nicholas J. Brandon, Jean-Christophe Rain, L. Miguel Camargo, Paul J. Whiting, Miles D. Houslay, Douglas H. R. Blackwood, Walter J. Muir, and David J. Porteous
Science 18 November 2005: 1187-1191.
Two genes associated with schizophrenia code for interacting proteins that modulate cyclic AMP metabolism, suggesting that this signaling pathway may contribute to the disorder Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Altered TCR Signaling from Geometrically Repatterned Immunological Synapses

Kaspar D. Mossman, Gabriele Campi, Jay T. Groves, and Michael L. Dustin
Science 18 November 2005: 1191-1193.
Manipulating the position of the antigen receptor within the immune synapse shows that receptors near the outside work best. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients

Matt Kaeberlein, R. Wilson Powers, III, Kristan K. Steffen, Eric A. Westman, Di Hu, Nick Dang, Emily O. Kerr, Kathryn T. Kirkland, Stanley Fields, and Brian K. Kennedy
Science 18 November 2005: 1193-1196.
A search of all yeast genes identifies two signaling enzymes belonging to a pathway that increases life span when calories are restricted. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Golgi Duplication in Trypanosoma brucei Requires Centrin2

Cynthia Y. He, Marc Pypaert, and Graham Warren
Science 18 November 2005: 1196-1198.
Published online 27 October 2005 [DOI: 10.1126/science.1119969] (in Science Express Reports)
A bi-lobed structure within cells contains an organelle-replication protein, which is required for duplication and faithful segregation of the Golgi complex to daughter cells. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|